The model, 23, also announced that she is selling her underwear on the site to some very lucky customers.
Lottie, who is the sister of supermodel Kate Moss, 47, told her fans that she offers “pantie purchases” in her first post.
She took to social media to share a stunning snap of her wearing a plunging black corset, teamed with lace stockings and a pair of skyscraper black high heels.
The blonde beauty smouldered at the camera while leaning back on a marble staircase.
She left little to the imagination as she put on a busty display and flashed a seductive glance.
Lottie posed up a storm at the luxury location, with opulent statues and pillars in the background.
The blonde shared the news that she had signed up to the the X-rated subscription site OnlyFan, writing: “Guess who just joined OF!!!”
The sultry pic left several fans hot under the collar, with one commenting: “Woah sign me up!”
Another posted: “🔥🔥100000 percent here for this. 🔥”
A third added: “You are so beautiful 😍.”
Lottie’s clearly not shy when it comes to flashing her assets, the model previously joined website Glow in February, a platform that allows users to sell provocative images of themselves to fans.
The star was just 13 when she was spotted by modelling scouts at supermodel Kate’s wedding to her now ex-husband Jamie Hince, 52, in 2011.
She then signed to the same agency as Kate, Storm models.
But she recently hinted that she was in a row with the agency after selling naked pictures on OnlyFans-style website Dream.
She said: “Kind of the reason why I’m not doing the modelling stuff is because I’m doing more nude stuff. I really enjoy it.
“I think it’s a shame the industry doesn’t kind of fully accept that.
“I’m not just talking about my agency – I’m talking about the industry as a whole, which doesn’t accept girls that do OnlyFans.
“Everyone kind of says, ‘Celebrate your body, do what you want with your body, whatever you wanna do with your life, you do it,’ but as soon as it’s OnlyFans and stuff like that, the industry is a bit iffy about it.”
But she has plenty to smile about after she recently boasted about earning £36,640 in just one month.
“Being able to create and monetize my content independently has allowed me to make a living in a much happier and healthier environment than the commercial modelling industry could ever provide,” Lottie said.
“No more stripping nude for free in front of creepy old men at castings, now I get to take the photos I want, when I want, wherever I want.”